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Identifying the Roles of Spatial Hallmarks in Tumor Progression and Therapeutic Response

2025 ASPIRE Award

Peter Sorger, PhD, Harvard Medical School

The Mark Foundation Center for Lineage Plasticity

Cory Abate-Shen, PhD, Anil Rustgi, MD, and Michael Shen, PhD, Columbia University Herbert Irving Comprehensive Cancer Center; David Solit, MD, Memorial Sloan Kettering Cancer Center

Therapeutic Targeting of Esophageal Tumors with MLL4 or UTX Mutations

2025 ASPIRE Award in Partnership with the DeGregorio Family Foundation and the Torrey Coast Foundation

Ali Shilatifard, PhD, Zibo Zhao, PhD, Northwestern University

Overcoming Immunosuppression and Immunotherapy Resistance in Gastric Cancer

2025 ASPIRE Award in Partnership with the DeGregorio Family Foundation and the Torrey Coast Foundation

Zheng Chen MD, PhD; Alejandro Villarino, PhD; Yan Guo, PhD; Peter Hosein, MD; Oliver McDonald, MD, PhD, Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine

Epigenetic Profiling and Restoration of Immune Response to Target Gastroesophageal Cancer

2025 ASPIRE Award in Partnership with the DeGregorio Family Foundation and the Torrey Coast Foundation

Sarah Derks, MD, PhD, Amsterdam University Medical Center; Wilbert Zwart, PhD, The Netherlands Cancer Institute

Enabling Spatial Biomarker Discovery for Predicting Follicular Lymphoma Progression, Transformation, and Therapeutic Response

2025 ASPIRE Award in Partnership with the Follicular Lymphoma Foundation

Rong Fan, PhD, Mina Xu, MD, and Coraline Mlynarczyk, PhD, Yale School of Medicine and Yale School of Engineering & Applied Science

Comprehensive Cellular and Spatial Characterization of the Follicular Lymphoma Microenvironment and Its Association with Clinical Outcomes

2025 ASPIRE Award in Partnership with the Follicular Lymphoma Foundation

Michael Green, PhD, and Christopher Flowers, MD, The University of Texas MD Anderson Cancer Center

Decoding the Dynamic Interplay between Hepatic Metabolism, the Nervous System, and Immune Response in Cancer Cachexia

2025 Endeavor Award

Ayelet Erez, MD, PhD and Steffen Jung, PhD, Weizmann Institute of Science; Asya Rolls, PhD, Tel Aviv University; and Keren Yizhak, PhD, Technion

Full Spectrum Genetic Engineering of CAR T-Cells for Gastric Cancer

2025 Endeavor Award in Partnership with the Torrey Coast Foundation

Julia Carnevale, MD, Justin Eyquem, PhD, Alexander Marson, MD, PhD, Kole Roybal, PhD, and Gregory Allen, MD, PhD, University of California San Francisco; Karin Pelka, PhD, Gladstone Institutes

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Identifying the Roles of Spatial Hallmarks in Tumor Progression and Therapeutic Response

2025 ASPIRE Award

Peter Sorger, PhD, Harvard Medical School

The Mark Foundation Center for Lineage Plasticity

Cory Abate-Shen, PhD, Anil Rustgi, MD, and Michael Shen, PhD, Columbia University Herbert Irving Comprehensive Cancer Center; David Solit, MD, Memorial Sloan Kettering Cancer Center

Therapeutic Targeting of Esophageal Tumors with MLL4 or UTX Mutations

2025 ASPIRE Award in Partnership with the DeGregorio Family Foundation and the Torrey Coast Foundation

Ali Shilatifard, PhD, Zibo Zhao, PhD, Northwestern University

Overcoming Immunosuppression and Immunotherapy Resistance in Gastric Cancer

2025 ASPIRE Award in Partnership with the DeGregorio Family Foundation and the Torrey Coast Foundation

Zheng Chen MD, PhD; Alejandro Villarino, PhD; Yan Guo, PhD; Peter Hosein, MD; Oliver McDonald, MD, PhD, Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine

Epigenetic Profiling and Restoration of Immune Response to Target Gastroesophageal Cancer

2025 ASPIRE Award in Partnership with the DeGregorio Family Foundation and the Torrey Coast Foundation

Sarah Derks, MD, PhD, Amsterdam University Medical Center; Wilbert Zwart, PhD, The Netherlands Cancer Institute

Enabling Spatial Biomarker Discovery for Predicting Follicular Lymphoma Progression, Transformation, and Therapeutic Response

2025 ASPIRE Award in Partnership with the Follicular Lymphoma Foundation

Rong Fan, PhD, Mina Xu, MD, and Coraline Mlynarczyk, PhD, Yale School of Medicine and Yale School of Engineering & Applied Science

Comprehensive Cellular and Spatial Characterization of the Follicular Lymphoma Microenvironment and Its Association with Clinical Outcomes

2025 ASPIRE Award in Partnership with the Follicular Lymphoma Foundation

Michael Green, PhD, and Christopher Flowers, MD, The University of Texas MD Anderson Cancer Center

Decoding the Dynamic Interplay between Hepatic Metabolism, the Nervous System, and Immune Response in Cancer Cachexia

2025 Endeavor Award

Ayelet Erez, MD, PhD and Steffen Jung, PhD, Weizmann Institute of Science; Asya Rolls, PhD, Tel Aviv University; and Keren Yizhak, PhD, Technion

Full Spectrum Genetic Engineering of CAR T-Cells for Gastric Cancer

2025 Endeavor Award in Partnership with the Torrey Coast Foundation

Julia Carnevale, MD, Justin Eyquem, PhD, Alexander Marson, MD, PhD, Kole Roybal, PhD, and Gregory Allen, MD, PhD, University of California San Francisco; Karin Pelka, PhD, Gladstone Institutes